However, they contain different active ingredients and work in slightly different ways. Carvedilol is a non-selective beta-blocker and metoprolol is a beta-1 selective beta-blocker. Carvedilol and metoprolol are both highly effective medications when compared to placebo.
Carvedilol and metoprolol are similarly effective for increasing survival after a heart attack. Guidelines from the American College of Cardiology ACC and American Heart Association AHA recommend the use of either carvedilol, metoprolol succinate, or bisoprolol for patients with heart failure with reduced ejection fraction. Consult a healthcare provider for the best treatment option for your specific condition.
Beta-blockers are commonly used in pregnant women with heart conditions. However, there is no evidence that suggests that beta-blockers are completely safe or harmful during pregnancy. Both carvedilol and metoprolol may carry a risk of fetal harm. Consult a healthcare provider for medical advice before using a beta-blocker during pregnancy. There may be an increased risk of side effects when combining a beta-blocker with alcohol.
Taking carvedilol or metoprolol with alcohol may increase the risk of drowsiness, dizziness, and low blood pressure. Alcohol may also decrease the effectiveness of beta-blockers. Carvedilol may lower blood pressure more than metoprolol. This is because carvedilol has vasodilating properties that help relax blood vessels and lower blood pressure.
No studies have directly compared the blood pressure lowering effects of carvedilol and metoprolol. However, carvedilol may help prevent cardiovascular events more than metoprolol in hypertensive patients.
It is generally safe to switch beta-blockers if needed or as recommended by a healthcare provider. Depending on the beta-blocker, the switch can be immediate or the dose of the initial beta-blocker can be weaned while the dose of the new beta-blocker is gradually increased to a target dose.
Follow-up visits may be needed to assess the effectiveness of the new beta-blocker. The best replacement for carvedilol will depend on the condition being treated. There are only two medications FDA-approved to treat heart failure other than carvedilol: bisoprolol and metoprolol succinate.
Other examples of beta-blockers include atenolol, nebivolol, and propranolol. Possible alternatives to metoprolol succinate for treating heart failure include bisoprolol and carvedilol.
The better beta blocker will be the one that works best for you. Other factors may play a role in choosing a beta blocker, such as cost, side effects, and other medications you may be taking. Skip to main content Search for a topic or drug. Carvedilol vs. By Gerardo Sison, Pharm. Talk to your doctor or pharmacist if these side effects bother you or do not go away: feeling dizzy headaches feeling tired feeling or being sick nausea or vomiting cold fingers or toes Serious side effects It happens rarely, but some people have serious side effects when taking carvedilol.
Tell a doctor straight away if you have: nose bleeds that last for more than 10 minutes, unexplained bruising, or you bruise more easily than usual — these can be signs of low numbers of platelets in your blood thrombocytopenia high temperature, sore throat, mouth sores, toothache, flu-like symptoms — these can be signs of a low number of white blood cells leukopenia shortness of breath with a cough that gets worse when you exercise like walking up the stairs , swollen ankles or legs, chest pain, or an irregular heartbeat — these may be signs of other heart problems shortness of breath, wheezing and tightening of your chest — these can be signs of lung problems yellow skin or the whites of your eyes turn yellow — these can be signs of liver problems Serious allergic reaction In rare cases, it's possible to have a serious allergic reaction anaphylaxis to carvedilol.
Information: You can report any suspected side effect using the Yellow Card safety scheme. Visit Yellow Card for further information. What to do about: feeling dizzy — as your body gets used to carvedilol this side effect should wear off.
Do not drive or operate machinery until you feel OK again. Try to avoid alcohol as it'll make you feel worse. Ask your pharmacist to recommend a painkiller. Do not drink too much alcohol. Headaches usually go away after the first week of taking carvedilol.
Talk to your doctor if the headaches last more than a week or are severe. Do not drink any alcohol as this will make you feel more tired. It might help to take your carvedilol after a meal or snack. If you're being sick, try drinking small, frequent sips of water to avoid dehydration. Do not smoke or have drinks with caffeine, as this can make your blood vessels narrower and restrict your blood flow. Try wearing mittens they're warmer than gloves and warm socks.
Speak to your doctor if this side effect bothers you. Carvedilol and breastfeeding If your doctor or health visitor says that your baby is healthy, it's OK to take carvedilol while breastfeeding. Non-urgent advice: Tell your doctor if you're:. There are some medicines that can affect the way carvedilol works. Speak to your doctor if you have low blood sugar levels without getting any warning signs.
You should check your blood sugar after exercise, and follow usual advice about checking it before driving, or operating machinery. Important: Medicine safety Tell your doctor or pharmacist if you're taking any other medicines, including herbal medicines, vitamins or supplements. How does carvedilol work? How long does it take to work?
How long will I take it for? Can I take carvedilol for a long time? What will happen if I stop taking it? How does it compare with other medicines for high blood pressure? These include: ACE inhibitors such as ramipril and lisinopril angiotensin receptor blockers like losartan calcium channel blockers like amlodipine medicines that make you pee more diuretics like indapamide The medicine your doctor prescribes first depends on your age and ethnicity.
How does it compare with other medicines for chest pain and angina? There are lots of other medicines to prevent angina attacks.
They include: calcium channel blockers such as diltiazem and amlodipine nitrates like isosorbide mononitrate medicines such as ranolazine, nicorandil or ivabradine If carvedilol does not work for you, or you cannot take carvedilol or other beta blockers because of side effects, you may be able to switch to another medicine.
How does it compare with other medicines that treat heart failure? Will I need to stop carvedilol before surgery? Your doctor may advise you to stop taking carvedilol before surgery. Can I drink alcohol? Is there any food or drink I need to avoid? You can eat and drink normally while taking carvedilol. Eating a healthy, balanced diet can help your heart condition. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects.
This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history. Carvedilol oral tablet can interact with other medications, herbs, or vitamins you might be taking. Note: You can reduce your chances of drug interactions by having all of your prescriptions filled at the same pharmacy. That way, a pharmacist can check for possible drug interactions.
Taking certain heart rhythm drugs with carvedilol can cause more severe side effects. The combination may lower your heart rate or blood pressure, or worsen a heart blockage. Your doctor may watch you closely for side effects or adjust the dosage of carvedilol or your heart rhythm drug. Using clonidine with carvedilol can lower your blood pressure and heart rate even further. If you need both drugs, your doctor will watch you for low blood pressure and low heart rate.
This combination may lower your heart rate and blood pressure too much. Examples of other beta-blockers include:. If you take a calcium channel blocker with carvedilol, your doctor will monitor your blood pressure and heart rhythm.
Examples of these drugs include:. Using carvedilol with certain diabetes drugs can make these diabetes drugs lower your blood sugar levels further. Taking carvedilol with cyclosporine may increase the levels of cyclosporine in your body.
Your doctor may lower your dosage of cyclosporine and monitor you closely. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking. Taking it again could be fatal. Symptoms of an allergic reaction include:.
Tell your doctor about all of your allergies before starting this medication. Taking it again could be fatal cause death. Talk to your doctor before using alcohol while taking this medication. If you drink alcohol while taking carvedilol, your blood pressure may decrease to levels that are lower than normal. This can be dangerous. A single dose of carvedilol can be fatal in people with asthma. This may lead to serious side effects, such as dangerously low blood pressure or slow heart rate.
Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet. Many patients who have high blood pressure will not notice any signs of the problem.
In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well. Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.
This medicine comes with a patient information insert. Read and follow the instructions in the insert carefully. Ask your doctor if you have any questions. If you cannot swallow the extended-release capsule, you may open it and pour the medicine into a small amount of cold, soft food such as an applesauce.
Stir this mixture well and swallow it without chewing. The dose of this medicine will be different for different patients.
Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
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